PediRounds

Hypertonic saline 3% — paediatric dose

Weight-based dosing for Hypertonic saline 3% in children. Category: Fluid/Electrolyte.

Dose3–5 mL/kg over 10–20 min
Per kg3–5 mL/kg
Maximum250 mL
RouteIV

Clinical notes

Raised ICP / symptomatic hyponatraemia. Monitor Na+ rise.

Common questions

What is the dose of Hypertonic saline 3% in children?

3–5 mL/kg over 10–20 min. That is 3–5 mL/kg per dose.

What is the maximum Hypertonic saline 3% dose for a child?

The maximum single dose is 250 mL. Weight-based calculation should never exceed this ceiling.

How is Hypertonic saline 3% given?

Hypertonic saline 3% is given by IV.

About this page

Compiled from standard paediatric references. Verify against a current formulary and your local protocol.

Spotted something wrong? Report an error on this page — corrections from clinicians are welcome and are reviewed before any change is published.

Last reviewed 2026-08-12.