PediRounds

Ondansetron — paediatric dose

Weight-based dosing for Ondansetron in children. Category: GI.

Dose0.1–0.15 mg/kg (max 8 mg)
Per kg0.1–0.15 mg/kg
Maximum8 mg
RouteIV/PO
Frequency8H prn

Clinical notes

QT prolongation at higher doses.

Common questions

What is the dose of Ondansetron in children?

0.1–0.15 mg/kg (max 8 mg). That is 0.1–0.15 mg/kg per dose.

What is the maximum Ondansetron dose for a child?

The maximum single dose is 8 mg. Weight-based calculation should never exceed this ceiling.

How is Ondansetron given?

Ondansetron is given by IV/PO, 8H prn.

About this page

Compiled from standard paediatric references. Verify against a current formulary and your local protocol.

Spotted something wrong? Report an error on this page — corrections from clinicians are welcome and are reviewed before any change is published.

Last reviewed 2026-08-12.