PediRounds

Prostaglandin E1 (alprostadil) — paediatric dose

Weight-based dosing for Prostaglandin E1 (alprostadil) in children. Category: Infusion.

Dose0.01–0.05 mcg/kg/min
Per kg0.01–0.05 mcg/kg/min/kg
RouteIV

Clinical notes

Maintains ductal patency. Apnoea – be ready to intubate.

Common questions

What is the dose of Prostaglandin E1 (alprostadil) in children?

0.01–0.05 mcg/kg/min. That is 0.01–0.05 mcg/kg/min/kg per dose.

How is Prostaglandin E1 (alprostadil) given?

Prostaglandin E1 (alprostadil) is given by IV.

About this page

Compiled from standard paediatric references. Verify against a current formulary and your local protocol.

Spotted something wrong? Report an error on this page — corrections from clinicians are welcome and are reviewed before any change is published.

Last reviewed 2026-08-12.