Protamine — paediatric dose
Weight-based dosing for Protamine in children. Category: Anticoagulant.
| Dose | 1 mg per 100 U of heparin in the last dose (max 50 mg); reduce for elapsed time |
|---|---|
| Maximum | 50 mg |
| Route | slow IV |
Clinical notes
Hypotension / anaphylactoid reaction if given rapidly.
Common questions
What is the dose of Protamine in children?
1 mg per 100 U of heparin in the last dose (max 50 mg); reduce for elapsed time.
What is the maximum Protamine dose for a child?
The maximum single dose is 50 mg. Weight-based calculation should never exceed this ceiling.
How is Protamine given?
Protamine is given by slow IV.
About this page
Compiled from standard paediatric references. Verify against a current formulary and your local protocol.
Spotted something wrong? Report an error on this page — corrections from clinicians are welcome and are reviewed before any change is published.
Last reviewed 2026-08-12.