Acute severe asthma
Paediatric emergency management · Breathing · Respiratory
Assess severity by work of breathing, air entry, SpO₂ and conscious level. Give high-flow oxygen to keep SpO₂ ≥94%.
Bronchodilators & steroid
- Salbutamol: nebulised 2.5 mg (<5 yr) / 5 mg (≥5 yr), back-to-back or continuous in severe cases.
- Add nebulised ipratropium 250 mcg with the first doses.
- Oral prednisolone 1–2 mg/kg or IV hydrocortisone 4 mg/kg.
Escalation
- IV magnesium sulfate 25–50 mg/kg (max 2 g) over 20 min.
- Consider IV salbutamol load then infusion, or aminophylline – with cardiac and electrolyte monitoring.
- HFNC / NIV; intubate only if exhausted or deteriorating (high risk – experienced operator).
Common questions
What is the first step in acute severe asthma?
Assess severity by work of breathing, air entry, SpO₂ and conscious level. Give high-flow oxygen to keep SpO₂ ≥94%.
About this page
Compiled from standard paediatric references. Verify against a current formulary and your local protocol.
Spotted something wrong? Report an error on this page — corrections from clinicians are welcome and are reviewed before any change is published.
Last reviewed 2026-08-12.