Septic shock
Paediatric emergency management · Circulation · Emergency
Recognise early: fever/hypothermia, tachycardia, altered perfusion or mental state. Within the first hour: oxygen, access, cultures, broad-spectrum antibiotics.
Resuscitation bundle
- Isotonic fluid 10–20 mL/kg boluses, reassessing for fluid overload after each (10 mL/kg where cardiac dysfunction likely).
- Empirical antibiotics within the first hour – do not delay for cultures.
- Measure lactate and glucose; correct hypoglycaemia and hypocalcaemia.
Fluid-refractory shock
- Start adrenaline or noradrenaline (peripheral dilute or central) – do not wait for a central line.
- Consider stress-dose hydrocortisone if catecholamine-resistant / suspected adrenal insufficiency.
Common questions
What is the first step in septic shock?
Recognise early: fever/hypothermia, tachycardia, altered perfusion or mental state. Within the first hour: oxygen, access, cultures, broad-spectrum antibiotics.
About this page
Compiled from standard paediatric references. Verify against a current formulary and your local protocol.
Spotted something wrong? Report an error on this page — corrections from clinicians are welcome and are reviewed before any change is published.
Last reviewed 2026-08-12.