PediRounds

Cholera vaccine

Oral Cholera Vaccine · IAP (risk-based)

When to giveEndemic / outbreak / travel. From 1 year of age.
Dose1.5 mL orally. Killed bivalent (O1 and O139) whole-cell V. cholerae.
RouteOral
SiteOral
Schedule / interval2 doses 2 weeks apart. Booster after 3 years may be considered.

Catch-up schedule

Complete the 2-dose primary series ≥2 weeks apart; no restart needed if delayed.

Adverse events (AEFI)

Well tolerated; occasional mild GI upset. Efficacy ~60%.

Brands available in India

Shanchol

Special considerations

Risk-based use only (travellers to/residents of endemic areas, outbreaks). Store 2–8°C.

See the full IAP-ACVIP 2025 immunisation schedule →

Sources

  • IAP-ACVIP Recommended Immunization Schedule 2025 (Indian Pediatrics 2026)
  • IAP Purple Book 2025, 5th edition