PediRounds

JE vaccine

Japanese Encephalitis vaccine · IAP / NIS (endemic)

When to giveEndemic areas. Live-attenuated (SA 14-14-2): Dose 1 at 9 mo, Dose 2 at 16–18 mo.
DoseLive SA 14-14-2: 0.5 mL SC, 5.4 log PFU. Inactivated Vero-cell (JEEV): 3 µg (1–3 yr) / 6 µg (3–18 yr), 0.5 mL IM. Inactivated Kolar strain: 5 µg / 0.5 mL IM, 2 doses.
RouteSubcutaneous (live) / Intramuscular (inactivated)
SiteThigh / deltoid
Schedule / intervalLive: 2 doses (9 mo & 16–18 mo). Inactivated: 2 doses 4 wk apart.

Catch-up schedule

Given in endemic districts after campaign; complete per product schedule.

Adverse events (AEFI)

Mild local reaction; fever, headache. >90% seroconversion.

Brands available in India

Live: SA 14-14-2. Inactivated: JEEV (SA 14-14-2 Vero-cell), JENVAC / JE-Shield (Kolar strain)

Special considerations

Only recommended in endemic regions or for travellers to endemic areas. Store 2–8°C. Live vaccine avoided in immunodeficiency.

Common questions

When is the JE vaccine given?

Endemic areas. Live-attenuated (SA 14-14-2): Dose 1 at 9 mo, Dose 2 at 16–18 mo.

What is the JE vaccine dose and route?

Live SA 14-14-2: 0.5 mL SC, 5.4 log PFU. Inactivated Vero-cell (JEEV): 3 µg (1–3 yr) / 6 µg (3–18 yr), 0.5 mL IM. Inactivated Kolar strain: 5 µg / 0.5 mL IM, 2 doses. Route: Subcutaneous (live) / Intramuscular (inactivated). Site: Thigh / deltoid.

Can the JE vaccine be given late?

Given in endemic districts after campaign; complete per product schedule.

What are the side effects of the JE vaccine?

Mild local reaction; fever, headache. >90% seroconversion.

Which JE vaccine brands are available in India?

Live: SA 14-14-2. Inactivated: JEEV (SA 14-14-2 Vero-cell), JENVAC / JE-Shield (Kolar strain)

See the full IAP-ACVIP 2025 immunisation schedule →

About this page

Reviewed by Dr Santanu Ghosh — MBBS, MD Paediatrics (Army), IDPCCM (IAP, ICH Kolkata). Paediatrician and paediatric critical care specialist.

Aligned with the IAP-ACVIP Recommended Immunization Schedule 2025 and compiled from standard paediatric references. Verify against the current product insert, the national schedule and your local protocol.

Spotted something wrong? Report an error on this page — corrections from clinicians are welcome and are reviewed before any change is published.

Last reviewed 2026-08-12.