JE vaccine
Japanese Encephalitis vaccine · IAP / NIS (endemic)
| When to give | Endemic areas. Live-attenuated (SA 14-14-2): Dose 1 at 9 mo, Dose 2 at 16–18 mo. |
|---|---|
| Dose | Live SA 14-14-2: 0.5 mL SC, 5.4 log PFU. Inactivated Vero-cell (JEEV): 3 µg (1–3 yr) / 6 µg (3–18 yr), 0.5 mL IM. Inactivated Kolar strain: 5 µg / 0.5 mL IM, 2 doses. |
| Route | Subcutaneous (live) / Intramuscular (inactivated) |
| Site | Thigh / deltoid |
| Schedule / interval | Live: 2 doses (9 mo & 16–18 mo). Inactivated: 2 doses 4 wk apart. |
Catch-up schedule
Given in endemic districts after campaign; complete per product schedule.
Adverse events (AEFI)
Mild local reaction; fever, headache. >90% seroconversion.
Brands available in India
Live: SA 14-14-2. Inactivated: JEEV (SA 14-14-2 Vero-cell), JENVAC / JE-Shield (Kolar strain)
Special considerations
Only recommended in endemic regions or for travellers to endemic areas. Store 2–8°C. Live vaccine avoided in immunodeficiency.
See the full IAP-ACVIP 2025 immunisation schedule →
Sources
- IAP-ACVIP Recommended Immunization Schedule 2025 (Indian Pediatrics 2026)
- IAP Purple Book 2025, 5th edition