TCV vaccine
Typhoid Conjugate Vaccine · IAP
| When to give | Single dose from 6 mo (can be given with MMR). |
|---|---|
| Dose | 0.5 mL IM. Vi-CPS 25 µg conjugated to tetanus toxoid (or CRM197 for Enteroshield) per 0.5 mL. |
| Route | Intramuscular |
| Site | Thigh / deltoid |
| Schedule / interval | Single primary dose at ≥6 months. Booster policy evolving. |
Catch-up schedule
Single catch-up dose at any age above 6 months if not previously given.
Adverse events (AEFI)
Mild local pain/swelling; transient fever. >90% seroconversion; efficacy 80–87% over 2 years.
Brands available in India
Typbar-TCV (Bharat Biotech), Enteroshield, Zyvac-TCV, TyphiBEv, Biovac-TCV
Special considerations
Preferred over older Vi-polysaccharide (Typbar, VacTyph, Bio-Typh — needs age ≥2 yr, revaccination every 3 yr). Store 2–8°C, do not freeze.
Common questions
When is the TCV vaccine given?
Single dose from 6 mo (can be given with MMR).
What is the TCV vaccine dose and route?
0.5 mL IM. Vi-CPS 25 µg conjugated to tetanus toxoid (or CRM197 for Enteroshield) per 0.5 mL. Route: Intramuscular. Site: Thigh / deltoid.
Can the TCV vaccine be given late?
Single catch-up dose at any age above 6 months if not previously given.
What are the side effects of the TCV vaccine?
Mild local pain/swelling; transient fever. >90% seroconversion; efficacy 80–87% over 2 years.
Which TCV vaccine brands are available in India?
Typbar-TCV (Bharat Biotech), Enteroshield, Zyvac-TCV, TyphiBEv, Biovac-TCV
See the full IAP-ACVIP 2025 immunisation schedule →
About this page
Aligned with the IAP-ACVIP Recommended Immunization Schedule 2025 and compiled from standard paediatric references. Verify against the current product insert, the national schedule and your local protocol.
Spotted something wrong? Report an error on this page — corrections from clinicians are welcome and are reviewed before any change is published.
Last reviewed 2026-08-12.