Hib vaccine
Haemophilus influenzae type b · IAP / NIS
| When to give | Primary at 6, 10, 14 wk; Booster at 15–18 mo. |
|---|---|
| Dose | 0.5 mL. Hib PRP (conjugate) 10 µg, conjugated to tetanus toxoid. |
| Route | Intramuscular |
| Site | Anterolateral mid-thigh |
| Schedule / interval | 6/10/14 wk; booster 15–18 mo. |
Catch-up schedule
Number of doses depends on age at start; not needed routinely after 5 years in healthy children.
Adverse events (AEFI)
Mild local reactions; low-grade fever. Serious AEFI rare.
Brands available in India
Usually as combinations — Quadrovax, COMVAC-4, EasyFour-TT (DTwP-Hib); Pentavac, Easyfive-TT, COMBE Five, COMVAC-5 (penta)
Special considerations
Almost always given as part of pentavalent (DTwP-HepB-Hib) vaccine. Store 2–8°C, do not freeze.
Common questions
When is the Hib vaccine given?
Primary at 6, 10, 14 wk; Booster at 15–18 mo.
What is the Hib vaccine dose and route?
0.5 mL. Hib PRP (conjugate) 10 µg, conjugated to tetanus toxoid. Route: Intramuscular. Site: Anterolateral mid-thigh.
Can the Hib vaccine be given late?
Number of doses depends on age at start; not needed routinely after 5 years in healthy children.
What are the side effects of the Hib vaccine?
Mild local reactions; low-grade fever. Serious AEFI rare.
Which Hib vaccine brands are available in India?
Usually as combinations — Quadrovax, COMVAC-4, EasyFour-TT (DTwP-Hib); Pentavac, Easyfive-TT, COMBE Five, COMVAC-5 (penta)
See the full IAP-ACVIP 2025 immunisation schedule →
About this page
Aligned with the IAP-ACVIP Recommended Immunization Schedule 2025 and compiled from standard paediatric references. Verify against the current product insert, the national schedule and your local protocol.
Spotted something wrong? Report an error on this page — corrections from clinicians are welcome and are reviewed before any change is published.
Last reviewed 2026-08-12.