Tdap / Td vaccine
Tetanus, reduced diphtheria, acellular pertussis · IAP / NIS
| When to give | Tdap single dose at 10–12 yr (irrespective of prior Tdap). Td at 10 & 16 yr (NIS). |
|---|---|
| Dose | 0.5 mL IM. Tdap: TT ≥5 Lf, reduced DT <2.5 Lf, acellular PT 8 µg, FHA 8 µg, pertactin 2.5 µg (Boostrix); Adacel has PT 2.5 µg, FHA 5 µg, PRN 3 µg. Td: TT 5 Lf, DT 2 Lf. |
| Route | Intramuscular |
| Site | Upper arm (deltoid) / thigh |
| Schedule / interval | Adolescent dose 10–12 yr; then Td boosters every 10 yr. |
Catch-up schedule
Recommended up to 18 years. Age 7–10 y not fully immunised → Tdap as first dose, then Td. If Tdap unavailable, substitute Td.
Adverse events (AEFI)
Local pain/redness/swelling; low-grade fever, malaise. Much less intense than DTwP. Efficacy ~90%.
Brands available in India
Tdap: Boostrix (GSK), Adacel (Sanofi). Td: Tdvac, BE-Td. TT: BE-TT
Special considerations
Also recommended in every pregnancy (27–36 wk) for maternal & neonatal pertussis protection. Contraindicated with encephalopathy after a previous dose. Store 2–8°C, do not freeze.
Common questions
When is the Tdap / Td vaccine given?
Tdap single dose at 10–12 yr (irrespective of prior Tdap). Td at 10 & 16 yr (NIS).
What is the Tdap / Td vaccine dose and route?
0.5 mL IM. Tdap: TT ≥5 Lf, reduced DT <2.5 Lf, acellular PT 8 µg, FHA 8 µg, pertactin 2.5 µg (Boostrix); Adacel has PT 2.5 µg, FHA 5 µg, PRN 3 µg. Td: TT 5 Lf, DT 2 Lf. Route: Intramuscular. Site: Upper arm (deltoid) / thigh.
Can the Tdap / Td vaccine be given late?
Recommended up to 18 years. Age 7–10 y not fully immunised → Tdap as first dose, then Td. If Tdap unavailable, substitute Td.
What are the side effects of the Tdap / Td vaccine?
Local pain/redness/swelling; low-grade fever, malaise. Much less intense than DTwP. Efficacy ~90%.
Which Tdap / Td vaccine brands are available in India?
Tdap: Boostrix (GSK), Adacel (Sanofi). Td: Tdvac, BE-Td. TT: BE-TT
See the full IAP-ACVIP 2025 immunisation schedule →
About this page
Aligned with the IAP-ACVIP Recommended Immunization Schedule 2025 and compiled from standard paediatric references. Verify against the current product insert, the national schedule and your local protocol.
Spotted something wrong? Report an error on this page — corrections from clinicians are welcome and are reviewed before any change is published.
Last reviewed 2026-08-12.