PediRounds

IPV vaccine

Inactivated Polio Vaccine · IAP / NIS

When to giveAt 6, 10, 14 wk; boosters at 15–18 mo and 4–6 yr.
Dose0.5 mL IM/SC (full dose) or 0.1 mL ID (fractional, ×2). Salk strain: Type 1 40 D-antigen U, Type 2 8 DU, Type 3 32 DU.
RouteIntramuscular / SC (or intradermal fractional)
SiteThigh / deltoid (IM); right upper arm (ID fractional)
Schedule / interval6, 10, 14 wk; boosters 15–18 mo & 4–6 yr. Min 4 wk between primaries.

Catch-up schedule

Resume without restarting; observe minimum 4-week interval between primary doses.

Adverse events (AEFI)

Mild local reactions; occasional low-grade fever. Efficacy 95–100%.

Brands available in India

Poliovac; also within combinations (Easyfour-Pol, Tetraxim, Pentaxim, EasySix, Hexasiil, Hexaxim, Infanrix Hexa)

Special considerations

IPV can be given as part of a combination vaccine. Preferred over OPV in immunocompromised children. Store 2–8°C, do not freeze.

Common questions

When is the IPV vaccine given?

At 6, 10, 14 wk; boosters at 15–18 mo and 4–6 yr.

What is the IPV vaccine dose and route?

0.5 mL IM/SC (full dose) or 0.1 mL ID (fractional, ×2). Salk strain: Type 1 40 D-antigen U, Type 2 8 DU, Type 3 32 DU. Route: Intramuscular / SC (or intradermal fractional). Site: Thigh / deltoid (IM); right upper arm (ID fractional).

Can the IPV vaccine be given late?

Resume without restarting; observe minimum 4-week interval between primary doses.

What are the side effects of the IPV vaccine?

Mild local reactions; occasional low-grade fever. Efficacy 95–100%.

Which IPV vaccine brands are available in India?

Poliovac; also within combinations (Easyfour-Pol, Tetraxim, Pentaxim, EasySix, Hexasiil, Hexaxim, Infanrix Hexa)

See the full IAP-ACVIP 2025 immunisation schedule →

About this page

Aligned with the IAP-ACVIP Recommended Immunization Schedule 2025 and compiled from standard paediatric references. Verify against the current product insert, the national schedule and your local protocol.

Spotted something wrong? Report an error on this page — corrections from clinicians are welcome and are reviewed before any change is published.

Last reviewed 2026-08-12.