PediRounds

IPV vaccine

Inactivated Polio Vaccine · IAP / NIS

When to giveAt 6, 10, 14 wk; boosters at 15–18 mo and 4–6 yr.
Dose0.5 mL IM/SC (full dose) or 0.1 mL ID (fractional, ×2). Salk strain: Type 1 40 D-antigen U, Type 2 8 DU, Type 3 32 DU.
RouteIntramuscular / SC (or intradermal fractional)
SiteThigh / deltoid (IM); right upper arm (ID fractional)
Schedule / interval6, 10, 14 wk; boosters 15–18 mo & 4–6 yr. Min 4 wk between primaries.

Catch-up schedule

Resume without restarting; observe minimum 4-week interval between primary doses.

Adverse events (AEFI)

Mild local reactions; occasional low-grade fever. Efficacy 95–100%.

Brands available in India

Poliovac; also within combinations (Easyfour-Pol, Tetraxim, Pentaxim, EasySix, Hexasiil, Hexaxim, Infanrix Hexa)

Special considerations

IPV can be given as part of a combination vaccine. Preferred over OPV in immunocompromised children. Store 2–8°C, do not freeze.

See the full IAP-ACVIP 2025 immunisation schedule →

Sources

  • IAP-ACVIP Recommended Immunization Schedule 2025 (Indian Pediatrics 2026)
  • IAP Purple Book 2025, 5th edition